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Journal: Pain
Article Title: Long-term neuropathic pain behaviors correlate with synaptic plasticity and limbic circuit alteration: a comparative observational study in mice
doi: 10.1097/j.pain.0000000000002549
Figure Lengend Snippet: Gene expression profile in hippocampus and PFC of sham mice at 12 months compared with the 1-month animals. (A and D) Show the heatmap summarizing the global and distinct gene expression levels across the screening sets in hippocampus (A) and PFC (D), profiled by the results of low-density TaqMan-RT-qPCR array. The analysis was performed using GraphPad Prism software (version 7.05). (B and E) Show the expression levels of the significantly ( P < 0.05) deregulated genes between sham mice at 12 months and at 1 month in hippocampus (B) and PFC (E). Data are expressed as the mean ± SD. (C) Shows the Venn diagram representing the cross-comparison of deregulated genes within the screening sets. PFC, prefrontal cortex.
Article Snippet: Heatmap was constructed using the statistical
Techniques: Gene Expression, Quantitative RT-PCR, Software, Expressing, Comparison
Journal: Pain
Article Title: Long-term neuropathic pain behaviors correlate with synaptic plasticity and limbic circuit alteration: a comparative observational study in mice
doi: 10.1097/j.pain.0000000000002549
Figure Lengend Snippet: Gene expression profile comparison between SNI and sham mice coupled by brain area and injury duration. (A, C, E, and G) Show the heatmap summarizing the global and distinct gene expression levels across the screening sets in hippocampus (A) or PFC (C) of the 1-month SNI mice compared with sham animals and in hippocampus (E) or PFC (G) of the 12-month SNI mice compared with sham animals. The heatmaps were profiled based on the results of low-density TaqMan-RT-qPCR array, and the analysis was performed using GraphPad Prism software (version 7.05). (B, D, F, and H) Show the expression levels of the significantly ( P < 0.05) deregulated genes between the 1-month SNI and sham mice at hippocampal region (B) or at PFC (D) and between the 12-month SNI and sham mice at hippocampal region (F) or at PFC (H). Data are expressed as the mean ± SD. PFC, prefrontal cortex; SNI, spared nerve injury.
Article Snippet: Heatmap was constructed using the statistical
Techniques: Gene Expression, Comparison, Quantitative RT-PCR, Software, Expressing